In this chapter, experts in physics applied, inorganic chemistry or microbiology amongst other, will expose the advances and studies in the vaccines. We can stand out studies in the field of the epidemiology, the immunology (that they work with nanoestructuras to design a vaccine by means of immunological technicians) or genic therapy by means of vectors víricos. Besides, they apply bioinformátics methods for the design of synthetic vaccines (ICREA RESEARCH PROFESSOR), in the field of the microbiology is working in the vaccine MTBVAC against the tuberculosis that could substitute the current and in the preventive medicine, a project against the Flu To.