Number 105, coordinated by Juli Peretó and Manuel Porcar, focuses on the rules that govern scientific research. The latest issue of the magazine Mètode, addresses the issue of standards in science, with special emphasis on synthetic biology; an area that, both for its novelty and complexity, still finds resistance in the field of standardization. Besides, in this issue of Method you will also find several interviews and articles that will surely be interesting to you and, as always, the sections of regular collaborators.